GSM1382268[Accession] - GEO DataSets

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Items: 4

Select item 2000574131.

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. DNA methylation is an epigenetic modification associated with transcriptional repression of promoters and is essential for mammalian development. Establishment of DNA methylation is mediated by the de novo DNA methyltransferases DNMT3A and DNMT3B, whereas DNMT1 ensures maintenance of methylation through replication. Absence of these enzymes is lethal, and somatic mutations in these genes have been associated with several human diseases. more...

Organism:: Mus musculus

Type:: Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL13112 GPL16417
21 Samples

Download data: TAB, WIG

Series

Accession:: GSE57413

ID:: 200057413

PubMed Similar studies

Select item 2000574122.

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation [ChIP-Seq]

(Submitter supplied) DNA methylation is an epigenetic modification associated with transcriptional repression of promoters and is essential for mammalian development. Establishment of DNA methylation is mediated by the de novo DNA methyltransferases DNMT3A and DNMT3B, whereas DNMT1 ensures maintenance of methylation through replication. Absence of these enzymes is lethal, and somatic mutations in these genes have been associated with several human diseases. more...