GSM1446361[Accession] - GEO DataSets

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Items: 4

Select item 2000597931.

Dynamic profiling of the protein life cycle in response to pathogens

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Protein profiling by Mass Spec

Platforms:: GPL18998 GPL17021
116 Samples

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Accession:: GSE59793

ID:: 200059793

PubMed Full text in PMC Similar studies

Select item 2000597842.

Dynamic profiling of the protein life cycle in response to pathogens (RNA-seq)

(Submitter supplied) Protein expression is regulated by production and degradation of mRNAs and proteins, but their specific relationships remain unknown. We combine measurements of protein production and degradation and mRNA dynamics to build a quantitative genomic model of the differential regulation of gene expression in LPS stimulated mouse dendritic cells. Changes in mRNA abundance play a dominant role in determining most dynamic fold changes in protein levels. more...