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Items: 3

1.

Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation

(Submitter supplied) Artificial transcription factors (ATFs) and genomic nucleases based on a DNA binding platform consist- ing of multiple zinc finger domains are currently be- ing developed for clinical applications. However, no genome-wide investigations into their binding speci- ficity have been performed. We have created six- finger ATFs to target two different 18 nt regions of the human SOX2 promoter; each ATF is constructed such that it contains or lacks a super KRAB do- main (SKD) that interacts with a complex contain- ing repressive histone methyltransferases. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
25 Samples
Download data: BED, GFF, TXT
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

HA_ChIP_552-SKD_rep2

Organism:
Homo sapiens
Source name:
Human breast adenocarcinoma cell-line MCF7
Platform:
GPL11154
Series:
GSE59980
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Sample
Accession:
GSM1462960
ID:
301462960
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