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Items: 3

1.

Cooperativity, specificity and evolutionary stability of Polycomb targeting in Drosophila

(Submitter supplied) We report the evolutionary behaviour of Polycomb group proteins, their recruitment factors and their underlying sequences by performing ChIP-seq analysis in 4-5 different Drosophila species. We demonstrate an extremely high conservation of Polycomb repressive domains across Drosophila species We validate few cases of PRE divergence that shows that cis-driven PRE evolution is a rare event. We further show that PHO recruitment to Polycomb domains is evolutionarily robust to motif changes and that PRC1 stabilizes binding of its key recruiter
Organism:
Drosophila melanogaster; Drosophila pseudoobscura; Drosophila simulans; Drosophila yakuba; Drosophila virilis
Type:
Genome binding/occupancy profiling by high throughput sequencing
6 related Platforms
70 Samples
Download data: BED, BEDGRAPH, TXT
Series
Accession:
GSE60428
ID:
200060428
2.

Illumina Genome Analyzer IIx (Drosophila simulans)

Organism:
Drosophila simulans
4 Series
21 Samples
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Platform
Accession:
GPL17484
ID:
100017484
3.

PH Sim Rep1

Organism:
Drosophila simulans
Source name:
D. Simulans_PH
Platform:
GPL17484
Series:
GSE60428
Download data
Sample
Accession:
GSM1479920
ID:
301479920
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db=gds|term=GSM1479920[Accession]|query=12|qty=6|blobid=MCID_6737df34d8d15c362519efd6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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