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Items: 3

1.

Decoding the regulatory network of early blood development from single-cell gene expression measurements.

(Submitter supplied) Reconstruction of the molecular pathways controlling organ development has been hampered by a lack of methods to resolve embryonic progenitor cells. Here we describe a strategy to address this problem that combines gene expression profiling of large numbers of single cells with data analysis based on diffusion maps for dimensionality reduction and network synthesis from state transition graphs. Applying the approach to hematopoietic development in the mouse embryo, we map the progression of mesoderm toward blood using single-cell gene expression analysis of 3,934 cells with blood-forming potential captured at four time points between E7.0 and E8.5. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
15 Samples
Download data: XLS
Series
Accession:
GSE61470
ID:
200061470
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

Neural Plate 4

Organism:
Mus musculus
Source name:
Flk1+ mesoderm
Platform:
GPL17021
Series:
GSE61470
Download data
Sample
Accession:
GSM1505550
ID:
301505550
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db=gds|term=GSM1505550[Accession]|query=11|qty=2|blobid=MCID_672b8b04b70df60c4d430fdd|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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