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Items: 4

1.

Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL11002 GPL15103
17 Samples
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Series
Accession:
GSE62150
ID:
200062150
2.

Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast [RNA-Seq]

(Submitter supplied) Reprogramming of ES cells towards the trophoblast lineage, and specifally into self-renewing TS cells, can seemingly be achieved by manipulation of transcription factors such as Cdx2 and Oct4, or modulation of signalling cascades, notably Ras signalling. Here we analyze the arising cells from such treatment in detail for the efficiency and completeness of the reprogramming process. We find that the reprogrammed cells retain an epigenetic and transcriptional memory of their ES cell origin and are not equal to bona fide trophectoderm-derived TS cells.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15103
8 Samples
Download data: TXT
Series
Accession:
GSE62149
ID:
200062149
3.

Illumina HiSeq 1000 (Mus musculus)

Platform
Accession:
GPL15103
ID:
100015103
4.

iCdx2_ES_TC_plastic

Organism:
Mus musculus
Source name:
Embryonic Stem Cells
Platform:
GPL15103
Series:
GSE62149 GSE62150
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Sample
Accession:
GSM1520411
ID:
301520411
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db=gds|term=GSM1520411[Accession]|query=22|qty=2|blobid=MCID_672a37f59a6e6010c121e719|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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