(Submitter supplied) We used microarray hybridization to compare the total in vitro transcriptome of M. bovis and M. tuberculosis H37Rv. Our aim was to get a global view on the differences of gene expression between these pathogens as a mean to identify the genetic basis for their distinct phenotypes.Differential expression was detected in 258 genes, representing a 6% of the total genome. Of these, 13 genes were further confirmed by quantitative RT-PCR.
more...- Organism:
- Mycobacterium tuberculosis; Mycobacterium tuberculosis variant bovis
- Type:
- Expression profiling by array
- Platform:
- GPL4057
- 4 Samples
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