GSM1605715[Accession] - GEO DataSets

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Items: 4

Select item 2000657761.

Transcriptome profiling in knock-in mouse models of Huntington's disease [striatum; cortex; liver; tissue survey]

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL13112
1259 Samples

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Accession:: GSE65776

ID:: 200065776

PubMed Full text in PMC Similar studies

Select item 2000657732.

Transcriptome profiling in knock-in mouse models of Huntington's disease [Striatum_miRNA]

(Submitter supplied) Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that is characterized by motor, cognitive, and psychiatric alterations. The mutation responsible for this disease is an abnormally expanded and unstable CAG repeat within the coding region of the gene encoding huntingtin (Htt). Knock-in mouse models of HD with human exon 1 containing expanded CAG repeats inserted in the murine huntingtin gene (Hdh) provide a genetic reconstruction of the human causative mutation within the mouse model. more...