GEO DataSets

(Submitter supplied) Mycobacterial pathogens adapt to environmental stresses such as nutrient deprivation by entering a non-replicative antibiotic-tolerant state of persistence. Using a biochemically-validated data-driven approach, we identified an adaptive metabolic network underlying the mycobacterial response to starvation in M. tuberculosis, M. bovis BCG and M. smegmatis. All three species show a strong Mg+2-dependence for surviving complete nutrient deprivation, accompanied by a broad phenotypic antibiotic resistance. more...

Organism:

Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19889

15 Samples

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