(Submitter supplied) Whole blood gene expression was monitored in 85 samples using a Fluidigm nanoscale RT-qPCR array targeting 96 genes that we refer to as “blood informative transcripts” (BIT). There was no evidence for transcriptional changes prior to the appearance of blood stage parasite at day 12 or 13, at which time there was a strong interferon response and, unexpectedly, down-regulation of transcripts related to inflammation and innate immunity.
more...- Organism:
- Homo sapiens
- Type:
- Expression profiling by RT-PCR
- Platform:
- GPL19957
- 87 Samples
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