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Items: 4

1.

RAG Represents a Widespread Threat to the Lymphocyte Genome - (Mnase-seq)

(Submitter supplied) The RAG1 endonuclease, together with its cofactor RAG2, is essential for V(D)J recombination but is a potent threat to genome stability. The sources of RAG1 mistargeting and the mechanisms that have evolved to suppress it are poorly understood. Here, we report the surprising finding that RAG1 binds to thousands of sites in the genome of developing lymphocytes, primarily at active promoters and enhancers. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
12 Samples
Download data: BW
Series
Accession:
GSE69474
ID:
200069474

PubMed Full text in PMC Similar studies SRA Run Selector

2.

RAG Represents a Widespread Threat to the Lymphocyte Genome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL11154
51 Samples
Download data: BW, WIG
Series
Accession:
GSE69478
ID:
200069478

PubMed Full text in PMC Similar studies

3.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8397 Series
189357 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

4.

RAG2ko_thy_mm_TCRBetaTg_RNAseq C22

Organism:
Mus musculus
Source name:
thymocytes
Platform:
GPL13112
Series:
GSE69474 GSE69478
Download data: BW
Sample
Accession:
GSM1701777
ID:
301701777

SRA Run Selector

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db=gds|term=GSM1701777[Accession]|query=4|qty=3|blobid=MCID_6799f9e53ebf2117040c4a95|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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