GEO DataSets

(Submitter supplied) Puberty unmasks or accelerates nephropathies, including the nephropathy of diabetes mellitus (DM). A number of cellular systems implicated in the kidney disease of DM interweave, forming an interdependent functional web. We performed focused microarray analysis to test the hypothesis that one or more genes in the transforming growth factor beta (TGF-β) signaling system would be differentially regulated in male rats depending on the age of onset of DM. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS4038

Platform:

GPL1355

12 Samples

Download data: CEL, CHP

Analysis of cortex from adult and juvenile Sprague-Dawley males 6 weeks after injection of STZ to induce diabetes. Puberty unmasks or accelerates the diabetic nephropathy. Results provide insight into molecular mechanisms underlying pubertal acceleration or unmasking of kidney disease in diabetes.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 age, 2 disease state, 2 protocol sets

Platform:

GPL1355

Series:

GSE7253

12 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...

Organism:

Rattus norvegicus

107 DataSets

749 Series

13 Related Platforms

23057 Samples

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