GEO DataSets

(Submitter supplied) Missense mutations in the gene for the ubiquitously expressed superoxide dismutase-1 (SOD1) are one of the causes of familial amyotrophic lateral sclerosis (ALS), the most common adult onset motor neuron disease in humans killing selectively large motor neurons. Mice and rats overexpressing mutant SOD1 develop an adult onset neurodegenerative disease with hindlimb-paralysis and subsequent death similar to the human condition. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS2823

Platform:

GPL1355

9 Samples

Download data: CEL

Analysis of spinal cord motor neurons from embryonic day 14 transgenics expressing the human superoxide dismutase 1 (SOD1) G93A mutant protein. The SOD1-G93A transgenic is a model for amyotrophic lateral sclerosis (ALS). Results provide insight into the pathogenesis of ALS.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL1355

Series:

GSE7493

9 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...

Organism:

Rattus norvegicus

107 DataSets

749 Series

13 Related Platforms

23057 Samples

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