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Items: 3

1.

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

(Submitter supplied) We recently used in situ Hi-C to create kilobase-resolution 3D maps of mammalian genomes. Here, we combine these with new Hi-C, microscopy, and genome-editing experiments to study the physical structure of chromatin fibers, domains, and loops. We find that the observed contact domains are inconsistent with the equilibrium state for an ordinary condensed polymer. Combining Hi-C data and novel mathematical theorems, we show that contact domains are also not consistent with a fractal globule. more...
Organism:
Homo sapiens
Type:
Other
4 related Platforms
74 Samples
Download data: TXT
Series
Accession:
GSE74072
ID:
200074072

SRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
11982 Series
330701 Samples
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Platform
Accession:
GPL18573
ID:
100018573

3.

SanbornRao-2015-HIC038

Organism:
Homo sapiens
Source name:
haploid fibroblast-like
Platform:
GPL18573
Series:
GSE74072
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Sample
Accession:
GSM1909158
ID:
301909158

SRA Run Selector

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db=gds|term=GSM1909158[Accession]|query=1|qty=2|blobid=MCID_664f70fbd01e38019c9ec80d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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