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Items: 3

1.

Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes

(Submitter supplied) We recently used in situ Hi-C to create kilobase-resolution 3D maps of mammalian genomes. Here, we combine these with new Hi-C, microscopy, and genome-editing experiments to study the physical structure of chromatin fibers, domains, and loops. We find that the observed contact domains are inconsistent with the equilibrium state for an ordinary condensed polymer. Combining Hi-C data and novel mathematical theorems, we show that contact domains are also not consistent with a fractal globule. more...
Organism:
Homo sapiens
Type:
Other
4 related Platforms
74 Samples
Download data: TXT
Series
Accession:
GSE74072
ID:
200074072

SRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11830 Series
336732 Samples
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Platform
Accession:
GPL16791
ID:
100016791

3.

SanbornRao-2015-HIC045

Organism:
Homo sapiens
Source name:
haploid fibroblast-like
Platform:
GPL16791
Series:
GSE74072
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Sample
Accession:
GSM1909165
ID:
301909165

SRA Run Selector

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db=gds|term=GSM1909165[Accession]|query=1|qty=2|blobid=MCID_66550053e795547e5fac3485|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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