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Items: 3

1.

N6-methyladenosine-Mediated Nuclear Export of Messenger RNA

(Submitter supplied) N6-methyladenosine (m6A) is the most common internal modification in eukaryotic messenger RNA (mRNA). The effects of this reversible cheimcal modification are mediated in part by methyl-specific RNA binding protein 'readers' of the YTH family. In this study we present the function of YTHDC1 (YT521) in promoting the export of mRNA from the nucleus to the cytoplasm. Additionally, we identify a role for YTHDC1 in exon retention in mouse embryonic stem cells (mESCs).
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL13112 GPL11154
38 Samples
Download data: BED, DIFF, TXT, XLSX
Series
Accession:
GSE74397
ID:
200074397
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

YTHDC1 PAR-CLIP Rep 2

Organism:
Homo sapiens
Source name:
HeLa transfected with YTHDC1-Flag
Platform:
GPL11154
Series:
GSE74397
Download data
Sample
Accession:
GSM1919503
ID:
301919503
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Supplemental Content

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