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Items: 3

1.

Chromosome 20q amplification regulates in vitro response to Kinesin-5 inhibitor

(Submitter supplied) We identified gene expression signatures predicting responsiveness to a Kinesin-5 (kinesin spindle protein, KIF11) inhibitor (Kinesin-5i) in cultured colon tumor cell lines. Genes predicting resistance to Kinesin-5i were enriched for those from chromosome 20q, a region of frequent amplification in a number of tumor types. siRNAs targeting genes in this chromosomal region identified AURKA, TPX2 and MYBL2 as genes whose disruption enhances response to Kinesin-5i. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL3992
29 Samples
Download data
Series
Accession:
GSE7969
ID:
200007969

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Functional ID v2.0 Array 1

(Submitter supplied) see manufacturer's website
Organism:
Homo sapiens
5 Series
140 Samples
Download data: TXT
Platform
Accession:
GPL3992
ID:
100003992

3.

CRC POOL vs. COLO201b

Organism:
Homo sapiens
Source name:
colon (channel 1) colon (channel 2)
Platform:
GPL3992
Series:
GSE7969
Download data
Sample
Accession:
GSM197262
ID:
300197262

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db=gds|term=GSM197262[Accession]|query=9|qty=2|blobid=MCID_67253cbdef89dc43ad776fb9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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