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Items: 3

1.

Integrator complex subunit 12 is a key regulator of human protein synthesis pathways

(Submitter supplied) Genome wide association studies of human lung function have identified a signal on 4q24 but the mechanistic basis for this signal is unclear. This region contains the Integrator Complex subunit 12 gene (INTS12) and nearby polymorphisms associated with lung function correlate with INTS12 expression. We aimed to define INTS12 function in human bronchial epithelial cells. RNAseq pathway analyses of INTS12 depleted cells revealed robust downregulation of several protein synthesis related pathways, including the aminoacyl tRNA synthetases and PERK regulated gene expression. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11154 GPL18573
27 Samples
Download data: NARROWPEAK, TXT, WIG
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

48h_untransfected_3

Organism:
Homo sapiens
Source name:
48h_untransfected
Platform:
GPL11154
Series:
GSE80386
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Sample
Accession:
GSM2125493
ID:
302125493
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db=gds|term=GSM2125493[Accession]|query=1|qty=2|blobid=MCID_6697ce388e4788294a57dc3f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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