GSM215334[Accession] - GEO DataSets

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Items: 4

Select item 2000086861.

Gene expression profiling in three primary human cell lines treated with atorvastatin or an inhibitor of Rho kinase

(Submitter supplied) Inhibitors of Rho kinase (ROCK) are a new class of drugs with potential benefit in oncology, neurology, and fibrotic and cardiovascular diseases. ROCK inhibitors modulate many cellular functions, some of which are similar to the pleiotropic (non-lipid lowering) effects of statins, suggesting additive or synergistic properties. Studies to date have used compounds which inhibit both isoforms of ROCK, ROCK1 and ROCK2. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2987
Platform:: GPL2507
36 Samples

Download data: TXT

Series

Accession:: GSE8686

ID:: 200008686

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 29872.

Comparison of Rho kinase inhibitor and atorvastatin effects on primary cell lines

Analysis of three primary cell lines treated with Rho kinase (ROCK) 2 inhibitor SLx-2119 or with atorvastatin. Effects of ROCK inhibitors overlap to some extent with the pleiotropic (nonlipid lowering) effects of statins. Results suggest possible synergistic effects between the two classes of drugs.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 agent, 3 cell line sets

Platform:: GPL2507
Series:: GSE8686
36 Samples

Download data: TXT

DataSet

Accession:: GDS2987

ID:: 2987

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000025073.

Sentrix Human-6 Expression BeadChip

(Submitter supplied) The Sentrix Human-6 BeadChip can be used to study expression of over 47,000 human transcripts. Researchers can generate whole-genome expression profiles for 6 samples in parallel on a single BeadChip. Array is composed of 3 micron features with average feature redundancy of 30-fold . All features are QCed by sequential hybridizations process called array decoding. Probes are fully screened all-full-length 50-mers. more...