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Items: 3

1.

Coordinated Activities of Multiple Myc-Dependent and Myc-Independent Biosynthetic Pathways in Hepatoblastoma

(Submitter supplied) Hepatoblastoma (HB) is associated with aberrant activation of the b-catenin and Hippo/YAP signaling pathways. Over-expression of mutant b-catenin and YAP in mice induces HBs that express high levels of c-Myc (Myc). In light of recent observations that Myc in unnecessary for long-term hepatocyte proliferation, we have now examined its role in HB pathogenesis using the above model. While Myc was found to be dispensable for in vivo HB initiation it was necessary to sustain rapid tumor growth. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
18 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE87578
ID:
200087578
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

WT hepatocyte rep2

Organism:
Mus musculus
Source name:
hepatocyte
Platform:
GPL19057
Series:
GSE87578
Download data: FPKM_TRACKING
Sample
Accession:
GSM2334710
ID:
302334710
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db=gds|term=GSM2334710[Accession]|query=1|qty=2|blobid=MCID_669ed3f057bd0c1190c2cf00|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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