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Items: 3

1.

H3K4 Methylation-Mediated Memory of an Active Transcriptional State Impairs Nuclear Reprogramming

(Submitter supplied) Xenopus eggs can induce the reversal of differentiation processes of somatic cells. Yet, the egg is not fully efficient in reprogramming a differentiated nucleus, as certain genes retain a memory of gene expression of their somatic cell of origin. This is thought to be a reason for the low success rate of current cloning and reprogramming strategies. While previous studies addressed extensively the mechanisms that maintain an inactive state of genes (OFF-memory), we investigated the importance of memory of an active transcriptional state (ON-memory) in maintaining cell fate identity and on resistance to reprogramming. more...
Organism:
Xenopus laevis
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21046
77 Samples
Download data: BED, XLS
Series
Accession:
GSE92366
ID:
200092366
2.

Illumina HiSeq 1500 (Xenopus laevis)

Organism:
Xenopus laevis
5 Series
126 Samples
Download data
Platform
Accession:
GPL21046
ID:
100021046
3.

Ectoderm_NT_H3_3K4M_3 (Group6)

Organism:
Xenopus laevis
Source name:
NT ectoderm cells
Platform:
GPL21046
Series:
GSE92366
Download data: XLS
Sample
Accession:
GSM2428253
ID:
302428253
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db=gds|term=GSM2428253[Accession]|query=1|qty=2|blobid=MCID_6670cf80ce9c6e4cac319f2e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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