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Items: 3

1.

Molecular role of RNA helicases MVH and TDRD9 in PIWI slicing-triggered mammalian piRNA biogenesis and function

(Submitter supplied) PIWI-interacting RNAs (piRNAs) function in the nucleus and cytoplasm of animal germ cells to suppress mobile genetic elements. In the mouse male germline, biogenesis of MIWI2-bound nuclear piRNAs depends on endonuclease activity of cytosolic MILI, but the process is poorly understood. Here we use a mouse model expressing an artificial piRNA precursor to show that MILI slicing of the precursor generates a 16-nt by-product and a pre-piRNA intermediate that requires 3ʹ end processing to mature as a new piRNA. more...
Organism:
Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL13112
40 Samples
Download data: CSV, TXT
Series
Accession:
GSE95580
ID:
200095580
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

MVH +/KI;adult;MVH IP;longer RNAs;rep3

Organism:
Mus musculus
Source name:
testis
Platform:
GPL13112
Series:
GSE95580
Download data
Sample
Accession:
GSM2516711
ID:
302516711
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Supplemental Content

db=gds|term=GSM2516711[Accession]|query=19|qty=2|blobid=MCID_671fbbc63b96c12390228fad|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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