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Items: 3

1.

The energetics and physiological impact of cohesin extrusion

(Submitter supplied) Cohesin extrusion is thought to play a central role in establishing the architecture of mammalian genomes. However, extrusion has not been visualized in vivo, and thus, its functional impact and energetics are unknown. Using ultra-deep Hi-C, we show that loop domains form by a process that requires cohesin ATPases. Once formed, however, loops and compartments are maintained for hours without energy input. more...
Organism:
Homo sapiens; Mus musculus
Type:
Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
6 related Platforms
352 Samples
Download data: BED, BEDGRAPH, BW, HIC, NARROWPEAK, TXT
Series
Accession:
GSE98119
ID:
200098119
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

T7134_wt_mRNA_rep1

Organism:
Mus musculus
Source name:
Tumor 7134 cell
Platform:
GPL21493
Series:
GSE98119
Download data: BW
Sample
Accession:
GSM2587482
ID:
302587482
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