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Items: 3

1.

Enhanced base editing by co-expression of free uracil DNA glycosylase inhibitor

(Submitter supplied) Even the latest generation of base editor (BE3) causes unwanted indels and non-C-to-T substitutions, compromising the fidelity of base editing outcome. Here we report a enhanced base editing system. The enhanced base edting system decreased the formation of unintended indels and C-to-A/C-to-G substitutions, and increased the frequency of desired C-to-T substitution, thereby improving both the accuracy and efficiency of base editing.
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL18573 GPL20795 GPL16791
64 Samples
Download data: XLSX
Series
Accession:
GSE98685
ID:
200098685
2.

HiSeq X Ten (Homo sapiens)

Platform
Accession:
GPL20795
ID:
100020795
3.

BE3_UGI-M-3_2+eBE-S1-3_2

Organism:
Homo sapiens
Source name:
293FT cells
Platform:
GPL20795
Series:
GSE98685
Download data: XLSX
Sample
Accession:
GSM2609994
ID:
302609994
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