GSM2615885[Accession] - GEO DataSets

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Items: 4

Select item 2000988231.

Knockout of HDAC1 and HDAC2 in Microglia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

4 related Platforms
94 Samples

Download data: BW, CEL

Series

Accession:: GSE98823

ID:: 200098823

Select item 2000988222.

Constitutive and Tamoxifen inducible knockout of HDAC1 and HDAC2 in Microglia

(Submitter supplied) Hdac1 and 2 are important regulators of developmental processes. In this study we created microglia specific compound Hdac1 and Hdac2 knock out mice. Pre-natal ablation of both Hdac1 and 2 from microglia leads to reduced cell number and altered cell morphology. To investigate how Hdac1 and 2 knock out in microglia alters cellular gene expression profile we carried out RNA-seq analysis at different time points.