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Items: 3

1.

Gene Enrichment Analysis Reveals Major Regulators of Mycobacterium tuberculosis Gene Expression in Two Models of Antibiotic Tolerance

(Submitter supplied) The development of antibiotic tolerance is believed to be a major factor in the lengthy duration of current tuberculosis therapies. In the current study, we have modeled antibiotic tolerance in vitro by exposing Mycobacterium tuberculosis to two distinct stress conditions: progressive hypoxia and nutrient starvation [phosphate-buffered saline (PBS)]. We then studied the bacterial transcriptional response using RNA-seq and employed a bioinformatics approach to identify important transcriptional regulators, which was facilitated by a novel Regulon Enrichment Test (RET). more...
Organism:
Mycobacterium tuberculosis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18768
22 Samples
Download data: CSV, RPKM
Series
Accession:
GSE104599
ID:
200104599
2.

Illumina HiSeq 2000 (Mycobacterium tuberculosis)

Organism:
Mycobacterium tuberculosis
17 Series
185 Samples
Download data
Platform
Accession:
GPL18768
ID:
100018768
3.

rpoB-7H9_rep3

Organism:
Mycobacterium tuberculosis
Source name:
rpoB-7H9
Platform:
GPL18768
Series:
GSE104599
Download data: RPKM
Sample
Accession:
GSM2803958
ID:
302803958
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db=gds|term=GSM2803958[Accession]|query=1|qty=2|blobid=MCID_669d1e8856cb0a044ec3fe20|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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