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Items: 4

1.

The transcription factor c-Maf is a positive regulator of IL-10 with context-specific roles in CD4+ T cell effector function and in vivo consequences

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
150 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE106464
ID:
200106464

PubMed Full text in PMC Similar studies

2.

The transcription factor c-Maf is a positive regulator of IL-10 with context-specific roles in CD4+ T cell effector function and in vivo consequences [RNA-seq in vitro]

(Submitter supplied) CD4+ T cells differentiate into distinct subsets which produce unique patterns of cytokines to eradicate pathogens, alongside IL-10 which controls immune pathology. How Il10 expression is regulated alongside the subset-specific cytokines is unclear. Using transcriptional and epigenomic profiling of CD4+ T cells from TH1 (malaria), TH2 (allergy) and TH17 (autoimmunity) disease models, we show here that c-Maf, identified as the top candidate regulator of IL-10, directly induces IL-10 across all CD4+ T cell subsets, controlling pathology in TH1 and TH2-type responses. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
110 Samples
Download data: BW
Series
Accession:
GSE106463
ID:
200106463

PubMed Full text in PMC Similar studies SRA Run Selector

3.

Illumina HiSeq 2500 (Mus musculus)

Organism:
Mus musculus
11098 Series
299211 Samples
Download data
Platform
Accession:
GPL17021
ID:
100017021

4.

RNA_TH0_6hr_BR1_TR1

Organism:
Mus musculus
Source name:
TH0,6hr,in vitro
Platform:
GPL17021
Series:
GSE106463 GSE106464
Download data: BW
Sample
Accession:
GSM2837914
ID:
302837914

SRA Run Selector

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db=gds|term=GSM2837914[Accession]|query=15|qty=2|blobid=MCID_672d4ded5614fa63672ce8d2|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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