GSM2838947[Accession] - GEO DataSets

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Items: 4

Select item 2001064941.

Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL17225 GPL25575 GPL23689
59 Samples

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Series

Accession:: GSE106494

ID:: 200106494

PubMed Full text in PMC Similar studies

Select item 2001064922.

Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle (part 2)

(Submitter supplied) Centromeres are the regions of eukaryotic chromosomes where kinetochores are assembled and direct the correct segregation of chromosomes. Active centromeres are defined by presence of nucleosomes containing CENP-A, a histone H3 variant, which alone is sufficient to direct kinetochore assembly. Once assembled at a location CENP-A chromatin and the kinetochore is maintained at that location though a positive feedback loop where kinetochore proteins recruited by CENP-A promote deposition of new CENP-A following replication. more...