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Items: 4

1.

HDAC1/2 are required for microglia identity during development, homeostasis and neurodegeneration in a context-dependent manner [ChIP-seq constitutive knockout]

(Submitter supplied) Microglia as tissue macrophages of the central nervous system (CNS) provide immunological defense and contribute to the establishment and maintenance of CNS homeostasis. Several transcription factors have been described that regulate microglia development and its steady state form, however little is known about the epigenetic signals that control microglia function in vivo. Here, we employed constitutive and inducible mutagenesis in microglia to delete two class I histone deacetylases (HDACs), Hdac1 and 2. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13112
17 Samples
Download data: BW
Series
Accession:
GSE107436
ID:
200107436

PubMed Similar studies SRA Run Selector

2.

Knockout of HDAC1 and HDAC2 in Microglia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
94 Samples
Download data: BW, CEL
Series
Accession:
GSE98823
ID:
200098823

PubMed Similar studies Analyze with GEO2R

3.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8348 Series
188708 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

4.

25_HDAC1-2lox-HDAC2-2lox-Cx3cr1-Cre_H3K27ac

Organism:
Mus musculus
Source name:
HDAC1-2lox-HDAC2-2lox-Cx3cr1-Cre_H3K27ac
Platform:
GPL13112
Series:
GSE98823 GSE107436
Download data: BW
Sample
Accession:
GSM2867020
ID:
302867020

SRA Run Selector

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db=gds|term=GSM2867020[Accession]|query=10|qty=2|blobid=MCID_6733b1715c1af07374772bce|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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