GEO DataSets

(Submitter supplied) In E. faecalis OG1RF, disruption of the ahrC gene encoding a predicted ArgR family transcription factor results in a severe defect in biofilm formation in vitro, as well as significant attenuation of virulence in multiple experimental infection models. Using RNA-seq, we observed ahrC-dependent changes in expression of over 20 genes. AhrC-repressed genes included predicted determinants of arginine catabolism and several other metabolic genes and predicted transporters, while AhrC-activated genes included determinants involved in production of surface protein adhesins. more...

Organism:

Enterococcus faecalis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL23172 GPL24867

12 Samples

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