GSM3107860[Accession] - GEO DataSets

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Items: 4

Select item 2001134951.

Transcriptional plasticity, priming and commitment in hematopoietic lineages

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Other

Platform:: GPL19057
393 Samples

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Series

Accession:: GSE113495

ID:: 200113495

PubMed Similar studies

Select item 2001134942.

Transcriptional plasticity, priming and commitment in hematopoietic lineages [CRISP-seq]

(Submitter supplied) Differentiation of adult hematopoietic stem cells (HSC) constantly produces the cell types of the blood and immune system. The dynamics of this process and the hierarchy of downstream oligopotent stem cell differentiation remain controversial. Here we dissect hematopoietic progenitor populations in a minimally biased fashion using extensive single cell sampling from murine bone marrow. We characterize the HSC population, define its quiescent transcriptional program and validate it with label retaining assays and cytokine mediated stimulations. more...