GSM3136828[Accession] - GEO DataSets

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Items: 4

Select item 2001141761.

Molecular basis of neuronal subtype bias introduced by proneural factors Ascl1 and Neurog2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL19057
66 Samples

Download data: H5

Series

Accession:: GSE114176

ID:: 200114176

PubMed Full text in PMC Similar studies

Select item 2001141722.

Molecular basis of neuronal subtype bias introduced by proneural factors Ascl1 and Neurog2 (ChIP-seq)

(Submitter supplied) Basic helix-loop-helix (bHLH) proneural transcription factors (TFs) Ascl1 and Neurog2 are integral to the development of the nervous system. Here, we investigated the molecular mechanisms by which Ascl1 and Neurog2 control the acquisition of generic neuronal fate and impose neuronal subtype identity. Using direct neuronal programming of embryonic stem cells, we found that Ascl1 and Neurog2 regulate distinct targets by binding to largely different sets of sites. more...