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Items: 3

1.

Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Breast Cancer Bone Metastasis

(Submitter supplied) The presence of disseminated tumor cells in patient bone marrow (BM) aspirates predicts decreased recurrence-free survival, yet little is known about whether hematopoietic BM cells impact bone metastases. Here, we report that the BM can be rendered metastasis-suppressive by the bone-targeting bisphosphonate, zoledronic acid (ZA). In particular, ZA modulates hematopoietic myeloid/osteoclast progenitor cell (M/OCP) lineage potential to render them metastasis-suppressive. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
38 Samples
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Series
Accession:
GSE108250
ID:
200108250
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

CTL1: BM_RNASeq - Bone_Marrow No_treatment replicate_1

Organism:
Mus musculus
Source name:
Bone marrow
Platform:
GPL17021
Series:
GSE108250
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Sample
Accession:
GSM3142390
ID:
303142390
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db=gds|term=GSM3142390[Accession]|query=133|qty=2|blobid=MCID_671ed5efe158b40557a373a0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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