GSM317592[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2000126461.

Chromatin Signatures in Multipotent Human HSCs Indicate the Fate of Bivalent Genes during Differentiation

(Submitter supplied) Histone modifications have been implicated in stem cell maintenance and differentiation. We have analyzed genome-wide changes in gene expression and histone modifications during differentiation of multipotent human primary hematopoietic stem cells/progenitor cells (HSCs/HPCs) into erythrocyte precursors. Our data indicate that H3K4me1, H3K9me1, and H3K27me1 associate with enhancers of differentiation genes prior to their activation and correlate with basal expression, suggesting that these monomethylations are involved in the maintenance of activation potential required for differentiation. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL570 GPL9052
24 Samples

Download data: BED, CEL, CHP, TXT

Series

Accession:: GSE12646

ID:: 200012646

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000090522.

Illumina Genome Analyzer (Homo sapiens)

Organism:: Homo sapiens

587 Series
7908 Samples

Platform

Accession:: GPL9052

ID:: 100009052

Select item 3003175923.

Organism:: Homo sapiens

Source name:: CD36+ cells

Platform:: GPL9052
Series:: GSE12646

Download data: BED, TXT

Sample

Accession:: GSM317592

ID:: 300317592

SRA Run Selector

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