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Items: 5

1.

Gata3 acts alongside Cdx2 to promote trophoblast gene expression downstream of Tead4 during mouse development

(Submitter supplied) The first lineage decisions during mouse development lead to establishment of embryonic and extraembryonic tissues. The transcription factor Cdx2 plays a central role by repressing pluripotency genes, such as Oct4 and promoting trophoblast fate at the blastocyst stage. Here we show that the transcription factor Gata3 is coexpressed with Cdx2 in the blastocyst and that overexpression of Gata3 in embryonic stem cells is sufficient to induce expression of trophoblast genes. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS3948 GDS3949
Platform:
GPL1261
24 Samples
Download data: CEL, CHP
Series
Accession:
GSE12999
ID:
200012999
2.

Differentiation time course of trophoblast stem cells

(Submitter supplied) To characterized the changes in gene expression during the differentiation of TS cells. TS cells can be derived from two time point during embryogenesis, cell lines tested were from each of these time points. Keywords: time course
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
14 Samples
Download data: CEL, CHP
Series
Accession:
GSE12985
ID:
200012985
3.
Full record GDS3948

Trophoblast stem cell differentiation in vitro

Analysis of trophoblast stem (TS) cell lines TS3.5 and TS6.5 derived from 2 time points during embryogenesis (from blastocyst and E6.5 embryos, respectively) and differentiated over 6 days. Results provide insight into the molecular basis of trophoblast development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 cell line, 2 protocol, 7 time sets
Platform:
GPL1261
Series:
GSE12999
14 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3948
ID:
3948
4.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4541 Series
40 Related Platforms
58922 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
5.

TS 3.5 day 2

Organism:
Mus musculus
Source name:
TS cells differentiated day 2
Platform:
GPL1261
Series:
GSE12985 GSE12999
Dataset:
GDS3948
Download data: CEL, CHP
Sample
Accession:
GSM325438
ID:
300325438
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