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Items: 3

1.

Acetaminophen-induced gene expression profiles in sandwich-cultured primary rat hepatoctyes

(Submitter supplied) The frequent use of rodent hepatic in vitro systems in pharmacological and toxicological investigations challenges extrapolation of in vitro results to the situation in vivo and interspecies extrapolation from rodents to humans. The toxicogenomics approach may aid in evaluating relevance of these model systems for human risk assessment by direct comparison of toxicant-induced gene expression profiles and infers mechanisms between several systems. more...
Organism:
Homo sapiens; Rattus norvegicus
Type:
Expression profiling by array
Platforms:
GPL887 GPL890
33 Samples
Download data: TXT
Series
Accession:
GSE13465
ID:
200013465
2.

Agilent-011868 Rat Oligo Microarray G4130A (Feature Number version)

(Submitter supplied) This microarray contains representative sequences derived from rat RefSeq, high-quality public rat mRNA accessions, homologs to human and mouse RefSeq, EST clusters determined by a leading biopharmaceutical company and the Incyte Zooseq database as well as toxicology markers determined by the National Institute of Environmental Health Sciences (NIEHS) and others. Many of the toxicology markers used in the design of this microarray were released to the public domain for the first time and will be used on this unique microarray product. more...
Organism:
Rattus norvegicus
9 DataSets
30 Series
1 Related Platform
1093 Samples
Download data: TXT
Platform
Accession:
GPL890
ID:
100000890
3.

Heps_Mod_APAP10_rat2

Organism:
Rattus norvegicus
Source name:
primary hepatocytes, sandwich-cultured, 10 mM APAP, 24h (channel 1) primary hepatocytes, sandwich-cultured, non-exposed (channel 2)
Platform:
GPL890
Series:
GSE13465
Download data: TXT
Sample
Accession:
GSM339442
ID:
300339442
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