GSM351754[Accession] - GEO DataSets

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Items: 4

Select item 2000141051.

Down syndrome study

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2872
9 Samples

Download data: GPR

Series

Accession:: GSE14105

ID:: 200014105

Select item 2000140212.

Transcriptional analysis of E12.5 telencephalon from 152F7 transgenic mouse

(Submitter supplied) The molecular mechanisms that lead to the cognitive defects characteristic of Down syndrome (DS), the most frequent cause of mental retardation, have remained elusive. Here we use a transgenic DS mouse model to show that DYRK1A gene dosage imbalance deregulates chromosomal clusters of genes located near neuron-restrictive silencer factor (REST/NRSF) binding sites. We found that DYRK1A binds the SWI/SNF-complex known to interact with REST/NRSF. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL2872
4 Samples

Download data: GPR

Series

Accession:: GSE14021

ID:: 200014021

Select item 1000028723.

Agilent-012694 Whole Mouse Genome G4122A (Feature Number version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. Arrays of this design have barcodes that begin with 16012694 or 2512694. more...