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Items: 3

1.

RNA sequencing of blood-brain barrier (BBB) microvessels from mice with orthotopic GBM showing the benefit of triple therapy combining anti-immune checkpoint therapy with dual-anti angiogenic therapy.

(Submitter supplied) Glioblastoma multiforme (GBM) is a non T cell-inflamed cancer characterized by an immunosuppressive microenvironment that impedes dendritic cell maturation and T cell cytotoxicity. The alleviation of immunosuppression might be a prerequisite for succesful immune checkpoint therapy in GBM. We here combine anti-angiogenic and immune checkpoint therapy and demonstrate improved therapeutic efficacy in syngeneic, orthotopic GBM models. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
15 Samples
Download data: TXT
Series
Accession:
GSE130324
ID:
200130324
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

Sham_3

Organism:
Mus musculus
Source name:
Brain microvessels from sham operated healthy mice
Platform:
GPL19057
Series:
GSE130324
Download data
Sample
Accession:
GSM3736168
ID:
303736168
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db=gds|term=GSM3736168[Accession]|query=2|qty=2|blobid=MCID_673cd695809a7b4aef17430c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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