GSM3780672[Accession] - GEO DataSets

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Items: 4

Select item 2001316321.

Genome-wide analysis of histone 3 lysine K27 acetylation and differential expression analysis in stem-like breast cancer cells in response to HDAC1/3/7 inhibition or knockdown

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
18 Samples

Download data: BIGWIG, TXT

Series

Accession:: GSE131632

ID:: 200131632

PubMed Similar studies

Select item 2001314362.

Genome-wide analysis of histone 3 lysine K27 acetylation in stem-like breast cancer cells in response to HDAC1/3/7 inhibition.

(Submitter supplied) We sought to investigate the effects of HDAC1 and HDAC7 inhibition on genome-wide histone 3 lysine 27 acetylation (H3K27ac) in BPLER cells, a stem-like breast cancer (BrCa) cell model (please search for keyword "BPLER" in GEO to access over 30 associated datasets). Treatment of BPLER cells with MS-275 (Entinostat), a HDAC1 and HDAC3 specific inhibitor, specifically downregulates HDAC7 mRNA and protein. more...