GSM381166[Accession] - GEO DataSets

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Items: 3

Select item 2000153281.

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection

(Submitter supplied) Pathogenic mycobacteria have the ability to survive within macrophages and persist inside granulomas composed of host immune cells. The complex host-pathogen interactions that determine the outcome of a mycobacterial infection process result in marked alterations of the host gene expression profile. Here we used the zebrafish model to investigate the specificity of the host response to infections with two mycobacterium strains that give distinct disease outcomes: an acute disease with early lethality or a chronic disease with granuloma formation, caused by Mycobacterium marinum strains Mma 20 and E11, respectively. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL7735
39 Samples

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Accession:: GSE15328

ID:: 200015328

Select item 1000077352.

LU/IBL_D.rerio_44k_015747

(Submitter supplied) The micro-array slides were custom designed by Agilent Technologies. The slides contain in total 43.371 probes of a 60 oligonucleotide length. Of these probes a total of 21.496 probes were identical to the probes present on the Agilent probe set that is commercially available under catalog number 013223_D. Most of the additional probes were designed using the eArray software from Agilent Technologies (https://earray.chem.agilent.com/earray/). more...