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Items: 3

1.

Analysis of the transcriptomic changes in murine small and large intestinal organoids after the sudden expression of BRAFV600E and/or p53R172H

(Submitter supplied) BRAFV600E confers poor prognosis and a distinct molecular type of colorectal cancer, which is often associated with TP53 alterations. In order to understand how BRAFV600E and p53R172H promote tumorigenesis in the intestinal epithelium, we generated murine organoids harboring conditional BraffloxV600E and/or Trp53LSL-R172H alleles and conducted RNA sequencing analysis after sudden oncogene induction. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
24 Samples
Download data: TXT
Series
Accession:
GSE132551
ID:
200132551
2.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
3.

colon p53 off rep1

Organism:
Mus musculus
Source name:
colonic organoids
Platform:
GPL21103
Series:
GSE132551
Download data
Sample
Accession:
GSM3874547
ID:
303874547
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