GSM397312[Accession] - GEO DataSets

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Items: 4

Select item 2000158111.

ZMYM2/FGFR1, BCR/FGFR1 or BCR/ABL1 in human cord blood CD34+ cells reveals similar but distinct gene expression profiles

(Submitter supplied) The 8p11 myeloproliferative syndrome (EMS), also referred to as the stem cell leukemia/lymphoma syndrome, is a chronic myeloproliferative disorder that rapidly progresses into an acute leukemia. Molecularly, EMS is characterized by fusion of various partner genes to the FGFR1 gene, resulting in constitutive activation of the tyrosine kinase activity within FGFR1. The two most common fusion genes in human EMS are ZMYM2/FGFR1 (previously known as ZNF198/FGFR1) and BCR/FGFR1. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4046
Platform:: GPL570
12 Samples

Download data: CEL, CHP

Series

Accession:: GSE15811

ID:: 200015811

Select item 40462.

Fusion oncogenes ZMYM2/FGFR1, BCR/FGFR1 or BCR/ABL1 in cord blood CD34+ cells

Analysis of cord blood CD34+ cells transduced with MIG vector-ZMYM2/FGFR1, -BCR/FGFR1or -P210 BCR/ABL1. FGFR1 fusion oncogenes are associated with 8p11 myeloproliferative syndrome (EMS) and aggressive acute myeloid leukemia. Results provide insight into role of FGFR1 fusion oncogenes in EMS onset.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 4 genotype/variation sets

Platform:: GPL570
Series:: GSE15811
12 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4046

ID:: 4046

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...