GSM4048698[Accession] - GEO DataSets

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Items: 4

Select item 2001364451.

A comparison of evolutionary changes and constraints on gene regulation between fin and limb development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Chiloscyllium punctatum; Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL21273 GPL27153 GPL18480
43 Samples

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Accession:: GSE136445

ID:: 200136445

PubMed Full text in PMC Similar studies

Select item 2001364152.

A comparison of evolutionary changes and constraints on gene regulation between fin and limb development [ATAC-seq]

(Submitter supplied) We report time-series transcriptome of developing bamboo shark fin buds and mouse forelimb buds, and open chromatin regions of developing mouse forelimb buds. The major contributions of this study are 1) transcriptomic data with an accurate orthology map for a systematic comparison between the two species; 2) high quality chromatin accessibility data for mouse limb development; 3) discovery of mass heterochronic genes between fins and limbs; 4) hourglass-shaped conservation between fins and limbs, providing insights into a general trend of gene regulatory evolution.