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Items: 4

1.

LIN28B Regulates Transcription and Potentiates MYCN-induced Neuroblastoma in a let-7-independent Manner

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
22 Samples
Download data: WIG
Series
Accession:
GSE138743
ID:
200138743

PubMed Full text in PMC Similar studies

2.

LIN28B Regulates Transcription and Potentiates MYCN-induced Neuroblastoma in a let-7-independent Manner [ChIP-seq]

(Submitter supplied) LIN28B is highly expressed in neuroblastoma and promotes tumorigenesis at least in part through inhibition of let-7 microRNA biogenesis. Here, we report that overexpression of either wild-type LIN28B, or a LIN28B mutant that is unable to bind and inhibit let-7, accelerates the onset and increases the penetrance of MYCN-induced neuroblastoma, potentiates the invasion and migration of transformed sympathetic neuroblasts and drives the distant metastases in vivo. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
11 Samples
Download data: WIG
Series
Accession:
GSE138742
ID:
200138742

PubMed Full text in PMC Similar studies SRA Run Selector

3.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12534 Series
342121 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

4.

BE2C_Flag-LIN28Bwt_yDox_input

Organism:
Homo sapiens
Source name:
Neuroblastoma
Platform:
GPL18573
Series:
GSE138742 GSE138743
Download data: WIG
Sample
Accession:
GSM4118367
ID:
304118367

SRA Run Selector

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db=gds|term=GSM4118367[Accession]|query=14|qty=2|blobid=MCID_672a0cbb098d4d3459172b27|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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