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Items: 3

1.

Gene architecture and sequence composition underpin selective dependency of long RNAs on components of the nuclear export pathway

(Submitter supplied) The nuclear export pathway transports long RNAs produced in the nucleus to the cytoplasm. The core components of this pathway are thought to be required for export of virtually all polyadenylated RNAs. Here, we depleted different proteins that act in nuclear export in human cells, and quantified the transcriptome-wide consequences on RNA localization. Different genes exhibited substantially variable sensitivities, with depletion of NXF1 and TREX components causing some transcripts to become strongly retained in the nucleus while others were not affected. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL18573 GPL24676
141 Samples
Download data: BW, CSV, TXT, XLSX
Series
Accession:
GSE139151
ID:
200139151
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

siNT2_cyt_rep1

Organism:
Homo sapiens
Source name:
Cytoplasmic fraction, siNT control for siALY+UAP56 cells, rep1
Platform:
GPL18573
Series:
GSE139151
Download data: BW, TXT
Sample
Accession:
GSM4132108
ID:
304132108
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Supplemental Content

db=gds|term=GSM4132108[Accession]|query=3|qty=2|blobid=MCID_67103c11c7d3ca20d576e07f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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