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Items: 4

1.

Chromatin dynamics reveal circadian control of human in vitro islet maturation [ChIP-seq]

(Submitter supplied) Stem cell-derived tissues could transform disease research and therapy, yet most methods generate functionally immature products. We investigate how human stem cells differentiate into pancreatic islets in vitro by profiling DNA methylation, chromatin accessibility, and histone modification changes. We find that enhancer potential is reset upon lineage commitment, and show how pervasive epigenetic priming steers endocrine cell fates. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
21 Samples
Download data: BED
Series
Accession:
GSE140500
ID:
200140500
2.

Chromatin dynamics reveal circadian control of human in vitro islet maturation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL18573 GPL16791 GPL20301
169 Samples
Download data: BB, BED, TXT
Series
Accession:
GSE139817
ID:
200139817
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

PP2_WCE

Organism:
Homo sapiens
Source name:
HUES 8 hESC line
Platform:
GPL16791
Series:
GSE139817 GSE140500
Download data
Sample
Accession:
GSM4171653
ID:
304171653
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Supplemental Content

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