GEO DataSets

(Submitter supplied) Goals of the Study: 1. Assess the scope of arginine-responsive hepatic gene expression using in vitro rat models. 2. Compare normal and tumorigenic cells 3. Identify potentially novel genes and pathways that may be subject to amino acid (arginine) regulation Background: We previously reported that mRNA levels of the tumor associated glycoprotein amino acid transporter TA1/LAT1/ CD98 light chain arginine increase in normal hepatic cells under low arginine conditions while levels are constitutive and high in hepatic tumor cells. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS1622

Platform:

GPL1355

12 Samples

Download data: CEL, EXP, TIFF

Analysis of neoplastic hepatic cells subjected to arginine deprivation. Results identify arginine responsive genes that become unresponsive to arginine in tumorigenic cells.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 cell type, 2 stress sets

Platform:

GPL1355

Series:

GSE2275

12 Samples

Download data: CEL, EXP, TIFF

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...

Organism:

Rattus norvegicus

107 DataSets

749 Series

13 Related Platforms

23057 Samples

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