GSM4221051[Accession] - GEO DataSets

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Items: 4

Select item 2001405011.

Chromatin dynamics reveal circadian control of human in vitro islet maturation [WGBS]

(Submitter supplied) Stem cell-derived tissues could transform disease research and therapy, yet most methods generate functionally immature products. We investigate how human stem cells differentiate into pancreatic islets in vitro by profiling DNA methylation, chromatin accessibility, and histone modification changes. We find that enhancer potential is reset upon lineage commitment, and show how pervasive epigenetic priming steers endocrine cell fates. more...

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing

Platform:: GPL20301
8 Samples

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Accession:: GSE140501

ID:: 200140501

PubMed Similar studies SRA Run Selector

Select item 2001398172.

Chromatin dynamics reveal circadian control of human in vitro islet maturation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing