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Items: 4

1.

Chromatin dynamics reveal circadian control of human in vitro islet maturation [WGBS]

(Submitter supplied) Stem cell-derived tissues could transform disease research and therapy, yet most methods generate functionally immature products. We investigate how human stem cells differentiate into pancreatic islets in vitro by profiling DNA methylation, chromatin accessibility, and histone modification changes. We find that enhancer potential is reset upon lineage commitment, and show how pervasive epigenetic priming steers endocrine cell fates. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL20301
8 Samples
Download data: BB
Series
Accession:
GSE140501
ID:
200140501
2.

Chromatin dynamics reveal circadian control of human in vitro islet maturation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL18573 GPL16791 GPL20301
169 Samples
Download data: BB, BED, TXT
Series
Accession:
GSE139817
ID:
200139817
3.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
4.

SCbeta_WGBS_rep1

Organism:
Homo sapiens
Source name:
HUES 8 hESC line
Platform:
GPL20301
Series:
GSE139817 GSE140501
Download data: BB
Sample
Accession:
GSM4221051
ID:
304221051
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Supplemental Content

db=gds|term=GSM4221051[Accession]|query=1|qty=2|blobid=MCID_669d016e56cb0a044ec23998|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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