GEO DataSets

(Submitter supplied) Temporal expression profiling was utilized to define transcriptional regulatory pathways in vivo in a mouse muscle regeneration model. Potential downstream targets of MyoD were identified by temporal expression, promoter data base mining, and gel shift assays; Slug and calpain 6 were identified as novel MyoD targets. Slug, a member of the snail/slug family of zinc finger transcriptional repressors critical for mesoderm/ectoderm development, was further shown to be a downstream target by using promoter/reporter constructs and demonstration of defective muscle regeneration in Slug null mice. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS233 GDS234

Platforms:

GPL32 GPL81

66 Samples

Download data: CEL

Cardiotoxin injected into mouse gastrocnemius muscle to induce muscle regeneration. Muscles profiled at 27 time points (0-40 days) post-injection. Transcriptional regulatory pathways defined.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 6 time sets

Platform:

GPL32

Series:

GSE469

12 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The MG-U74 version 1 set comprises three arrays representing over 36,000 mouse genes and ESTs. more...

Organism:

Mus musculus

14 DataSets

24 Series

302 Samples

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