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Items: 3

1.

New Pathogenesis Mechanisms and Translational Leads Identified by Multidimensional Analysis of Necrotizing Myositis in Primates

(Submitter supplied) Purpose: We used dual RNA-seq to analyze the transcriptomes of serotype M1 S. pyogenes and host skeletal muscle recovered contemporaneously from infected nonhuman primates (NHPs). We identified genes important for necrotizing myositis, made isogenic deletion mutants and performed RNA-seq comparing one of those deletion mutant strains (dahA) grown in vitro and compared to its parental wild-type strain. more...
Organism:
Streptococcus pyogenes; Macaca fascicularis
Type:
Expression profiling by high throughput sequencing
4 related Platforms
54 Samples
Download data: XLSX
Series
Accession:
GSE144100
ID:
200144100
2.

NextSeq 550 (Macaca fascicularis; Streptococcus pyogenes)

Organism:
Streptococcus pyogenes; Macaca fascicularis
1 Series
18 Samples
Download data
Platform
Accession:
GPL28037
ID:
100028037
3.

Sample 10_nhp1_4_inf_raw

Organism:
Macaca fascicularis; Streptococcus pyogenes
Source name:
Skeletal muscle infected tissue section
Platform:
GPL28037
Series:
GSE144100
Download data
Sample
Accession:
GSM4279876
ID:
304279876

Supplemental Content

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